Discovery Services
The SERA platform can be utilized to identify antibody signatures for diagnostics, disease research and drug development.
Applications
Identification of Biomarkers in Cancer and Autoimmune
Immunogenicity and Anti-Drug Antibody
Vaccine Development
Disease Stratification
Infectious Disease Testing
SERA Library
Large universal library - 10 billion 12 mer sequences
Explore epitope diversity and immune response sub-types
Screen and identify disease specific antigens for any disease / organism
Compare samples to identify changes in antibody repertoire in response to disease, treatment, vaccination etc.
Discover epitopes from multiple organisms in the same assay
Large database of non-disease controls available
Ability to screen for novel antigen, epitopes
How it Works
Customer Provides:
50 ul of serum or plasma per sample.
Minimal information about the samples.
Serimmune analyzes each sample for IgG antibodies using its 10 billion member, random 12mer, bacterial peptide display library.
Serimmune performs epitope analysis across the entire proteome using its proprietary IMUNE and PIWAS methodologies.
Serimmune provides summary data and visualizations for each sample, including raw data for subsequent customer analysis.
Sample Requirements
Specimen
Serum, Plasma and CSF
Volume
100ul for Serum or Plasma, 150ul for CSF
Species
Any species with antibodies that are able to bind A/G beads
Storage
Samples may be stored for up to 2 weeks at 2-8°C or indefinitely if frozen
Shipping
Samples may be shipped overnight at ambient temperature
or shipped on wet ice. Blood or serum/plasma samples should be shipped in biohazardous material compliant packaging
Custom assays available upon request