SERA
Antibody Profiling Service
Broadly profile antibody repertoires and identify antigens and epitopes associated with cancer, autoimmune, infectious disease, drug response and more.
Why SERA Antibody Profiling?
Develop immune profile signatures to identify disease / antigen associations
Patient stratification - correlate immune response with clinical outcomes
High resolution - identify specific epitopes and motifs
View the diversity of the immune response across samples of interest
Sample Requirements
Specimen
Serum, Plasma and CSF
Volume
50 uL min sample volume (ideally 100uL for Serum or Plasma, 150ul for CSF)
Shipping
Samples may be shipped overnight at ambient temperature or shipped on wet ice. Blood or serum/plasma samples should be shipped in biohazardous material compliant packaging.
Species
Any species with antibodies that are able to bind A/G beads
Storage
Samples may be stored for up to 2 weeks at 2-8°C or indefinitely if frozen
Applications
SERA can be applied across multiple areas of research.
Oncology
Autoimmune
Vaccines
Infectious Disease
Selected Publications
Utilizing the Autoantibody Immune Response to Tumor Antigens for Kidney Cancer Early Detection. Poster, The Early Detection of Cancer Conference (2021)
Autoantibody Landscape in Patients with Advanced Prostate Cancer. Clinical Cancer Research (2020)
Antibody epitope repertoire analysis enables rapid antigen discovery and multiplex